Produced by an adipose tissue excess, rather of visceral type, RBP4 (Retinol Binding Protein type 4) promotes lipide deposits in peripheral tissues, liver, heart, arteries, injecting insulin resistance, inflammation, oxidative stress, through multiple mechanisms including an increased lipogenesis and a reduced mitochondrial fatty acids oxidation.

RBP4 plasma level is positively corretaled to the fatty liver degree and atheroma degree (measured by carotid and femoral intima thickness).

Actions of RBP4 on the body
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